Plasmalemmal VDAC-1 corroborated as amyloid Aß-receptor
نویسندگان
چکیده
منابع مشابه
Plasmalemmal VDAC-1 corroborated as amyloid Aß-receptor
Some 40 years ago while spending the night in front of TV and waiting for Neil Armstrong to step down the lander of Apollo 11 to the surface of the moon, indeed, I could not imagine to witness, another event of corresponding relevance for mankind in my lifetime. However, the recent report by Siemers and colleges on slowing down progress of Alzheimer Disease of people showing mild but proven Alz...
متن کاملVoltage dependent anion channel-1 (VDAC-1) as an anti-cancer target.
Voltage dependent anion channels (VDACs) are pore-forming proteins (approximately 30 kDa) associated with mitochondria, the membrane-bound organelles found in almost all eukaryotes. Commonly referred to as the “power-generators of cells”, mitochondria are composed of binary membranes, an outer membrane (OMM; outer mitochondrial membrane) and an inner membrane (IMM; inner mitochondrial membrane)...
متن کاملAfter all, plasmalemmal expression of type-1 VDAC can be understood. Phosphorylation, nitrosylation, and channel modulators work together in vertebrate cell volume regulation and either apoptotic pathway
Citation: Thinnes FP (2015) After all, plasmalemmal expression of type-1 VDAC can be understood. Phosphorylation, nitrosylation, and channel modulators work together in vertebrate cell volume regulation and either apoptotic pathway. Front. Physiol. 6:126. doi: 10.3389/fphys.2015.00126 After all, plasmalemmal expression of type-1 VDAC can be understood. Phosphorylation, nitrosylation, and channe...
متن کاملComments on plasmalemmal vesicle associated protein-1 as a novel marker implicated in brain tumor angiogenesis.
To the Editor: We have read with great interest the November 1, 2005 article by Carson-Walter et al. (1) on plasmalemmal vesicle–associated protein 1 (PV-1; also called PLVAP) expression in malignant brain. The authors have shown that PLVAP is expressed in a subset of malignant and diseased brain tissue, is up-regulated by vascular endothelial growth factor (VEGF) and hepatocyte growth factor, ...
متن کاملThe topology of VDAC as probed by biotin modification.
The outer membrane of mitochondria contains channels called VDAC (mitochondrial porin), which are formed by a single 30-kDa protein. Cysteine residues introduced by site-directed mutagenesis at sites throughout Neurospora crassa VDAC (naturally devoid of cysteine) were specifically biotinylated prior to reconstitution into planar phospholipid membranes. From previous studies, binding of strepta...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2015
ISSN: 1663-4365
DOI: 10.3389/fnagi.2015.00188